Contrast Media Mechanisms - Video Lesson

Hey everyone. Welcome to today's lesson on gadolinium contrast media mechanisms. In this lesson, we will discuss key facts about gadolinium, linear and macrocyclic agents, how gadolinium acts when used as a T one agent, and how it acts when used as a T two agent. Let's get started. Gadolinium, a rare earth heavy metal ion, is the center of understanding gadolinium contrast media. Possessing seven unpaired electrons, it exhibits exceptionally strong paramagnetic properties. In its natural form, gadolinium is highly toxic to the human body. To render it safe for intravenous administration, it must be tightly bound or chelated to a ligand. Contemporary agents employ either linear or macrocyclic ligands. Linear agents or open chain agents have a chain shaped ligand that wraps around the